Best Practice Guide for Generating Mass Spectra
Authors: Vicki Barwick, John Langley, Tony Mallet, Bridget Stein, Ken Webb
Two key applications of mass spectrometry are the confirmation of the identity of known compounds (e.g. compounds produced from target synthesis) and the identification of unknown compounds. Both of these applications require the generation of reliable mass spectra. However, poor quality spectra can be misleading and may result in incorrect conclusions being drawn.
The ‘Best Practice Guide for Generating Mass Spectra’ takes the user, step-by-step, through the process of generating mass spectra that are fit for purpose. It also describes the main components of a mass spectrometer and the instrument checks that should be carried prior to the analysis of samples, as well as how to select the appropriate ionization mode.
Production of the guide was supported under contract with the Department of Trade and Industry as part of the National Measurement System Valid Analytical Measurement (VAM) programme.
The guide can be downloaded free of charge from the VAM website |